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Clotting Cascade And Anticoagulants

Posted on 10 March, 2018
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ppssppmaster.com -Clotting Cascade And Anticoagulants Key Points • Hemostasis requires the interaction of platelets, coagulation and fibrinolytic factors, endothelium, proinflammatory and anti-inflammatory mediators,

1. Drugs Affecting Coagulation And Anticoagulants

Drugs Affecting Coagulation And Anticoagulants  DownloadSource: www.slideshare.net

Clotting Cascade And Anticoagulants nown as clotting) is the process by which blood changes from a liquid to a gel, forming a blood clot. It potentially results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair.

Overview of the coagulation system. The concept of blood coagulation dates back to 1960's when Davie, Ratnoff and Macfarlane described the “waterfall” and “cascade” theories outlining the fundamental principle of cascade of proenzymes leading to activation of downstream enzymes.

Anticoagulant. Specifically, antiplatelet drugs inhibit platelet aggregation (clumping together), whereas anticoagulants inhibit the coagulation cascade by clotting factors that happens after the initial platelet aggregation.

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